Plant based traditional medicine systems are playing a vital role for health care in both developing and developed countries. Ayurveda, the traditional Indian holistic medicine, uses plant derived products for cancer care, is not merely a system of medicine. Rather, it is a way of life. Even with great advancements in treatment and control of cancer, western medicine has significant deficiencies such as dose-limiting toxicity and drug resistance. Moreover, the enormous search for novel compounds is escalating, in which Ayurveda with its huge active compound repository can lend a hand to find new potential leads. Currently, global population is widely accepting the Ayurvedic medicine as the plant based treatments can rescue the patients from adverse side effects of western medicine. The Ayurvedic science is believed to add a step on to the curative aspects of cancer and lead to healthy living by fostering healthy cells in addition to controlling/killing the cancer cells.